Protein name:
Cytotoxic and regulatory T-cell molecule ;
Alternative:
Class-I MHC-restricted T-cell-associated molecule ;
CD:
CD355 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CADM1.
Function:
Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MWWRVLSLLA | WFPLQEASLT | NHTETITVEE | GQTLTLKCVT | SLRKNSSLQW |
100:
LTPSGFTIFL | NEYPALKNSK | YQLLHHSANQ | LSITVPNVTL | QDEGVYKCLH |
150:
YSDSVSTKEV | KVIVLATPFK | PILEASVIRK | QNGEEHVVLM | CSTMRSKPPP |
200:
QITWLLGNSM | EVSGGTLHEF | ETDGKKCNTT | STLIIHTYGK | NSTVDCIIRH |
250:
RGLQGRKLVA | PFRFEDLVTD | EETASDALER | NSLSSQDPQQ | PTSTVSVTED |
300:
SSTSEIDKEE | KEQTTQDPDL | TTEANPQYLG | LARKKSGILL | LTLVSFLIFI |
350:
LFIIVQLFIM | KLRKAHVIWK | KENEVSEHTL | ESYRSRSNNE | ETSSEEKNGQ |
393:
SSHPMRCMNY | ITKLYSEAKT | KRKENVQHSK | LEEKHIQVPE | SIV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Cytotoxic and regulatory T-cell molecule
ELISA Kit for Human Cytotoxic and regulatory T-cell molecule
CLIA Kit for Human Cytotoxic and regulatory T-cell molecule
CLIA Kit for Human Cytotoxic and regulatory T-cell molecule
Polyclonal Antibody for Human Cytotoxic and regulatory T-cell molecule
Polyclonal Antibody for Human Cytotoxic and regulatory T-cell molecule
Monoclonal Antibody for Human Cytotoxic and regulatory T-cell molecule
Monoclonal Antibody for Human Cytotoxic and regulatory T-cell molecule
Protein for Human Cytotoxic and regulatory T-cell molecule
Protein for Human Cytotoxic and regulatory T-cell molecule
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;VARIANT ARG-321
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLY-368
tissue :
Peripheral blood .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH CADM1;TISSUE SPECIFICITY
5.
"Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule."
Galibert L.
,
Diemer G.S.
,
Liu Z.
,
Johnson R.S.
,
Smith J.L.
,
Walzer T.
,
Comeau M.R.
,
Rauch C.T.
,
Wolfson M.F.
,
Sorensen R.A.
,
Van der Vuurst de Vries A.-R.
,
Branstetter D.G.
,
Koelling R.M.
,
Scholler J.
,
Fanslow W.C.
,
Baum P.R.
,
Derry J.M.
,
Yan W.
J. Biol. Chem.280:21955-21964(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CADM1
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 18-117;DISULFIDE BOND